Divigel Basics
Divigel is a systemic estrogen therapy. It contains 17B-Estradiol and comes in 5 strengths: 0.25 mg, 0.5 mg, 1 mg.
Divigel should be applied once a day, at the same time each day.
Apply Divigel to clean, dry, and unbroken (without cuts or scrapes) skin. If you take a bath or shower, be sure to apply Divigel after your skin is dry. The application site should be dry before getting dressed or swimming. Creams or lotions should not be applied on top of Divigel.
Divigel is applied to your upper thigh. Alternate between your left and right thigh each day to help prevent skin irritation.
Gently spread the gel in a thin layer over an area of ~6 inches or 2 palm prints. It is not necessary to massage in.
Dispose of the empty Divigel packet in the trash.
Wash your hands with soap and water immediately after applying Divigel to reduce the chance of transferring Divigel to other people or pets.
Allow the gel to dry before getting dressed. This takes 10-15 minutes. Try to keep the area dry for as long as possible.
Do not allow another person to come in contact with the area of skin where you applied the gel for at least 1 hour after you apply Divigel.
Do not apply Divigel to your face, breast, in or around the vagina.
Divigel contains alcohol. Alcohol based gels are flammable. Avoid fire, flame or smoking until the gel has dried.
If you miss a dose, do not double the dose on the next day to catch up. If your next dose is less than 12 hours away, it is best just to wait and apply your normal dose the next day. If it is more than 12 hours until the next dose, apply the dose you missed and resume your normal dosing the next day. Do not apply Divigel more than 1-time each day. If you accidentally spill some of the contents of a Divigel packet, do not open a new Divigel packet. Wait and apply your normal dose the next day.
Divigel can cause symptoms of bloating, breast tenderness, headache, and nausea.
